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Biochemical and structural characterization of two cif-like epoxide hydrolases from Burkholderia cenocepacia
Epoxide hydrolases catalyze the conversion of epoxides to vicinal diols in a range of cellular processes such as signaling, detoxification, and virulence. These enzymes typically utilize a pair of tyrosine residues to orient the substrate epoxide ring in the active site and stabilize the hydrolysis...
Autores principales: | Taher, Noor M., Hvorecny, Kelli L., Burke, Cassandra M., Gilman, Morgan S.A., Heussler, Gary E., Adolf-Bryfogle, Jared, Bahl, Christopher D., O'Toole, George A., Madden, Dean R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244358/ https://www.ncbi.nlm.nih.gov/pubmed/34235487 http://dx.doi.org/10.1016/j.crstbi.2021.02.002 |
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