Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model

OBJECTIVE: Cerebral mitochondrial dysfunction is a key mediator of neurologic injury following cardiac arrest (CA) and is regulated by the balance of fusion and fission (mitochondrial dynamics). Under stress, fission can decrease mitochondrial mass and signal apoptosis, while fusion promotes oxidati...

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Detalles Bibliográficos
Autores principales: Senthil, Kumaran, Morgan, Ryan W., Hefti, Marco M., Karlsson, Michael, Lautz, Andrew J., Mavroudis, Constantine D., Ko, Tiffany, Nadkarni, Vinay M., Ehinger, Johannes, Berg, Robert A., Sutton, Robert M., McGowan, Francis X., Kilbaugh, Todd J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Experimental Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244484/
https://www.ncbi.nlm.nih.gov/pubmed/34223382
http://dx.doi.org/10.1016/j.resplu.2021.100124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244484/
https://www.ncbi.nlm.nih.gov/pubmed/34223382
http://dx.doi.org/10.1016/j.resplu.2021.100124

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