Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine

Immune response after a single dose of BNT162b2 vaccine was markedly increased in subjects with previous severe acute respiratory syndrome coronavirus 2 infection, reaching similar immunoglobulin titers to those elicited by the full 2 doses in naive cases, and increased modestly after the second dos...

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Autores principales: Velasco, María, Galán, Maria Isabel, Casas, Maria Luisa, Pérez-Fernández, Elia, Martínez-Ponce, Diana, González-Piñeiro, Beatriz, Castilla, Virgilio, Guijarro, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244747/
https://www.ncbi.nlm.nih.gov/pubmed/34258322
http://dx.doi.org/10.1093/ofid/ofab299
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author Velasco, María
Galán, Maria Isabel
Casas, Maria Luisa
Pérez-Fernández, Elia
Martínez-Ponce, Diana
González-Piñeiro, Beatriz
Castilla, Virgilio
Guijarro, Carlos
author_facet Velasco, María
Galán, Maria Isabel
Casas, Maria Luisa
Pérez-Fernández, Elia
Martínez-Ponce, Diana
González-Piñeiro, Beatriz
Castilla, Virgilio
Guijarro, Carlos
author_sort Velasco, María
collection PubMed
description Immune response after a single dose of BNT162b2 vaccine was markedly increased in subjects with previous severe acute respiratory syndrome coronavirus 2 infection, reaching similar immunoglobulin titers to those elicited by the full 2 doses in naive cases, and increased modestly after the second dose. These data may inform the priority of the boosting dose.
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spelling pubmed-82447472021-07-01 Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Velasco, María Galán, Maria Isabel Casas, Maria Luisa Pérez-Fernández, Elia Martínez-Ponce, Diana González-Piñeiro, Beatriz Castilla, Virgilio Guijarro, Carlos Open Forum Infect Dis Brief Report Immune response after a single dose of BNT162b2 vaccine was markedly increased in subjects with previous severe acute respiratory syndrome coronavirus 2 infection, reaching similar immunoglobulin titers to those elicited by the full 2 doses in naive cases, and increased modestly after the second dose. These data may inform the priority of the boosting dose. Oxford University Press 2021-06-04 /pmc/articles/PMC8244747/ /pubmed/34258322 http://dx.doi.org/10.1093/ofid/ofab299 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Velasco, María
Galán, Maria Isabel
Casas, Maria Luisa
Pérez-Fernández, Elia
Martínez-Ponce, Diana
González-Piñeiro, Beatriz
Castilla, Virgilio
Guijarro, Carlos
Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title_full Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title_fullStr Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title_full_unstemmed Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title_short Impact of Previous Coronavirus Disease 2019 on Immune Response After a Single Dose of BNT162b2 Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine
title_sort impact of previous coronavirus disease 2019 on immune response after a single dose of bnt162b2 severe acute respiratory syndrome coronavirus 2 vaccine
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244747/
https://www.ncbi.nlm.nih.gov/pubmed/34258322
http://dx.doi.org/10.1093/ofid/ofab299
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