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Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery

AIMS: Hydroxyapatite (HA)-coated collars have been shown to reduce aseptic loosening of massive endoprostheses following primary surgery. Limited information exists about their effectiveness in revision surgery. The aim of this study was to radiologically assess osteointegration to HA-coated collars...

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Autores principales: Davies, Benjamin, Kaila, Rajiv, Andritsos, Loukas, Gray Stephens, Christian, Blunn, Gordon W., Gerrand, Craig, Gikas, Panagiotis, Johnston, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244796/
https://www.ncbi.nlm.nih.gov/pubmed/34134510
http://dx.doi.org/10.1302/2633-1462.26.BJO-2021-0017.R1
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author Davies, Benjamin
Kaila, Rajiv
Andritsos, Loukas
Gray Stephens, Christian
Blunn, Gordon W.
Gerrand, Craig
Gikas, Panagiotis
Johnston, Andrew
author_facet Davies, Benjamin
Kaila, Rajiv
Andritsos, Loukas
Gray Stephens, Christian
Blunn, Gordon W.
Gerrand, Craig
Gikas, Panagiotis
Johnston, Andrew
author_sort Davies, Benjamin
collection PubMed
description AIMS: Hydroxyapatite (HA)-coated collars have been shown to reduce aseptic loosening of massive endoprostheses following primary surgery. Limited information exists about their effectiveness in revision surgery. The aim of this study was to radiologically assess osteointegration to HA-coated collars of cemented massive endoprostheses following revision surgery. METHODS: Retrospective review of osseointegration frequency, pattern, and timing to a specific HA-coated collar on massive endoprostheses used in revision surgery at our tertiary referral centre between 2010 to 2017 was undertaken. Osseointegration was radiologically classified on cases with a minimum follow-up of six months. RESULTS: In all, 39 patients underwent radiological review at mean 43.5 months; 22/39 (56.4%) showed no osseointegration to the collar. Revision endoprostheses for aseptic loosening were less likely to show osseointegration compared with other indications for revision. Oncological cases with previous or current infection were more likely to show osseointegration to ≥ 1 collar side than those without evidence of prior infection. CONCLUSION: This seven-year review identified osseointegration of HA-coated collars after revision surgery is less likely (43.6%, 17/39) than after primary surgery. Young patients who undergo revision surgery following initial oncological indication may benefit the most from this collar design. Use in revision oncological cases with a history of infection may be beneficial. HA-coated collars showed limited benefit for patients undergoing revision for failed arthroplasty with history of infection. Cite this article: Bone Jt Open 2021;2(6):371–379.
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spelling pubmed-82447962021-07-14 Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery Davies, Benjamin Kaila, Rajiv Andritsos, Loukas Gray Stephens, Christian Blunn, Gordon W. Gerrand, Craig Gikas, Panagiotis Johnston, Andrew Bone Jt Open Oncology AIMS: Hydroxyapatite (HA)-coated collars have been shown to reduce aseptic loosening of massive endoprostheses following primary surgery. Limited information exists about their effectiveness in revision surgery. The aim of this study was to radiologically assess osteointegration to HA-coated collars of cemented massive endoprostheses following revision surgery. METHODS: Retrospective review of osseointegration frequency, pattern, and timing to a specific HA-coated collar on massive endoprostheses used in revision surgery at our tertiary referral centre between 2010 to 2017 was undertaken. Osseointegration was radiologically classified on cases with a minimum follow-up of six months. RESULTS: In all, 39 patients underwent radiological review at mean 43.5 months; 22/39 (56.4%) showed no osseointegration to the collar. Revision endoprostheses for aseptic loosening were less likely to show osseointegration compared with other indications for revision. Oncological cases with previous or current infection were more likely to show osseointegration to ≥ 1 collar side than those without evidence of prior infection. CONCLUSION: This seven-year review identified osseointegration of HA-coated collars after revision surgery is less likely (43.6%, 17/39) than after primary surgery. Young patients who undergo revision surgery following initial oncological indication may benefit the most from this collar design. Use in revision oncological cases with a history of infection may be beneficial. HA-coated collars showed limited benefit for patients undergoing revision for failed arthroplasty with history of infection. Cite this article: Bone Jt Open 2021;2(6):371–379. The British Editorial Society of Bone & Joint Surgery 2021-06-17 /pmc/articles/PMC8244796/ /pubmed/34134510 http://dx.doi.org/10.1302/2633-1462.26.BJO-2021-0017.R1 Text en © 2021 Author(s) et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/.
spellingShingle Oncology
Davies, Benjamin
Kaila, Rajiv
Andritsos, Loukas
Gray Stephens, Christian
Blunn, Gordon W.
Gerrand, Craig
Gikas, Panagiotis
Johnston, Andrew
Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title_full Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title_fullStr Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title_full_unstemmed Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title_short Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
title_sort osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244796/
https://www.ncbi.nlm.nih.gov/pubmed/34134510
http://dx.doi.org/10.1302/2633-1462.26.BJO-2021-0017.R1
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