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Assembly principles and stoichiometry of a complete human kinetochore module

Centromeres are epigenetically determined chromosomal loci that seed kinetochore assembly to promote chromosome segregation during cell division. CENP-A, a centromere-specific histone H3 variant, establishes the foundations for centromere epigenetic memory and kinetochore assembly. It recruits the c...

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Detalles Bibliográficos
Autores principales: Walstein, Kai, Petrovic, Arsen, Pan, Dongqing, Hagemeier, Birte, Vogt, Dorothee, Vetter, Ingrid R., Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245036/
https://www.ncbi.nlm.nih.gov/pubmed/34193424
http://dx.doi.org/10.1126/sciadv.abg1037