Weakly acidic carboxy group-grafted β-cyclodextrin-threaded acid-degradable polyrotaxanes for modulating protein interaction and cellular internalization

To improve the therapeutic potential of β-cyclodextrin (β-CD)-threaded acid-degradable polyrotaxanes (β-CD PRXs) in cholesterol-related metabolic disorders, we investigated the effect of carboxylation of β-CD PRXs on intracellular uptake. In this study, we established a synthetic method for the modi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shunyao, Tamura, Atsushi, Yui, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Focus on Trends in Biomaterials in Japan
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245098/
https://www.ncbi.nlm.nih.gov/pubmed/34248421
http://dx.doi.org/10.1080/14686996.2021.1935315

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245098/
https://www.ncbi.nlm.nih.gov/pubmed/34248421
http://dx.doi.org/10.1080/14686996.2021.1935315

Ejemplares similares