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Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice
Increasing age is the strongest predictor of risk of COVID-19 severity and mortality. Immunometabolic switch from glycolysis to ketolysis protects against inflammatory damage and influenza infection in adults. To investigate how age compromises defense against coronavirus infection, and whether a pr...
Autores principales: | Ryu, Seungjin, Shchukina, Irina, Youm, Yun-Hee, Qing, Hua, Hilliard, Brandon, Dlugos, Tamara, Zhang, Xinbo, Yasumoto, Yuki, Booth, Carmen J, Fernández-Hernando, Carlos, Suárez, Yajaira, Khanna, Kamal, Horvath, Tamas L, Dietrich, Marcelo O, Artyomov, Maxim, Wang, Andrew, Dixit, Vishwa Deep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245129/ https://www.ncbi.nlm.nih.gov/pubmed/34151773 http://dx.doi.org/10.7554/eLife.66522 |
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