Pentoxifylline Enhances Antioxidative Capability and Promotes Mitochondrial Biogenesis in D-Galactose-Induced Aging Mice by Increasing Nrf2 and PGC-1α through the cAMP-CREB Pathway

Aging is a complex phenomenon associated with oxidative stress and mitochondrial dysfunction. The objective of this study was to investigate the potential ameliorative effects of the phosphodiesterase inhibitor pentoxifylline (PTX) on the aging process and its underlying mechanisms. We treated D-gal...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Zhang, Tianyun, Zhao, Hui, Qi, Chunxiao, Ji, Xiaoming, Yan, Hexin, Cui, Rui, Zhang, Guoliang, Kang, Yunxiao, Shi, Geming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245236/
https://www.ncbi.nlm.nih.gov/pubmed/34257818
http://dx.doi.org/10.1155/2021/6695613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245236/
https://www.ncbi.nlm.nih.gov/pubmed/34257818
http://dx.doi.org/10.1155/2021/6695613

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