Cargando…
Coexpression of Helios in Foxp3(+) Regulatory T Cells and Its Role in Human Disease
Regulatory T cells (Tregs) expressing the Foxp3 transcription factor are indispensable for the maintenance of immune system homeostasis. Tregs may lose Foxp3 expression or be reprogrammed into cells that produce proinflammatory cytokines, for example, Th1-like Tregs, Th2-like Tregs, Th17-like Tregs,...
Autores principales: | Yu, Wen-qing, Ji, Ning-fei, Gu, Cheng-jing, Wang, Yan-li, Huang, Mao, Zhang, Ming-shun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245237/ https://www.ncbi.nlm.nih.gov/pubmed/34257746 http://dx.doi.org/10.1155/2021/5574472 |
Ejemplares similares
-
Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios(+) and Helios(−) Cells Coexist within the Natural FOXP3(+) T Regulatory Cell Subset in Humans
por: Elkord, Eyad
Publicado: (2016) -
Co-expression of Foxp3 and Helios facilitates the identification of human T regulatory cells in health and disease
por: Morina, Lyra, et al.
Publicado: (2023) -
Downregulation of miR-4772-3p promotes enhanced regulatory T cell capacity in malignant pleural effusion by elevating Helios levels
por: Yu, Wen-Qing, et al.
Publicado: (2019) -
Clinical significance of expanded Foxp3(+) Helios(−) regulatory T cells in patients with non-small cell lung cancer
por: MUTO, SATOSHI, et al.
Publicado: (2015) -
Intratumoral FoxP3(+)Helios(+) Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
por: Syed Khaja, Azharuddin Sajid, et al.
Publicado: (2017)