Genetic predisposition in the 2′-5′A pathway in the development of type 1 diabetes: potential contribution to dysregulation of innate antiviral immunity

AIMS/HYPOTHESIS: The incidence of type 1 diabetes is increasing more rapidly than can be explained by genetic drift. Viruses may play an important role in the disease, as they seem to activate the 2′-5′-linked oligoadenylate (2′-5′A) pathway of the innate antiviral immune system. Our aim was to inve...

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Detalles Bibliográficos
Autores principales: Pedersen, Kristina, Haupt-Jorgensen, Martin, Krogvold, Lars, Kaur, Simranjeet, Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245375/
https://www.ncbi.nlm.nih.gov/pubmed/33973017
http://dx.doi.org/10.1007/s00125-021-05469-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245375/
https://www.ncbi.nlm.nih.gov/pubmed/33973017
http://dx.doi.org/10.1007/s00125-021-05469-5

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