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Importance of evaluating protein glycosylation in pluripotent stem cell-derived cardiomyocytes for research and clinical applications
Proper protein glycosylation is critical to normal cardiomyocyte physiology. Aberrant glycosylation can alter protein localization, structure, drug interactions, and cellular function. The in vitro differentiation of human pluripotent stem cells into cardiomyocytes (hPSC-CM) has become increasingly...
Autores principales: | Kelly, Maia I., Albahrani, Mustafa, Castro, Chase, Poon, Ellen, Yan, Bin, Littrell, Jack, Waas, Matthew, Boheler, Kenneth R., Gundry, Rebekah L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245383/ https://www.ncbi.nlm.nih.gov/pubmed/33830329 http://dx.doi.org/10.1007/s00424-021-02554-x |
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