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Importance of evaluating protein glycosylation in pluripotent stem cell-derived cardiomyocytes for research and clinical applications

Proper protein glycosylation is critical to normal cardiomyocyte physiology. Aberrant glycosylation can alter protein localization, structure, drug interactions, and cellular function. The in vitro differentiation of human pluripotent stem cells into cardiomyocytes (hPSC-CM) has become increasingly...

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Detalles Bibliográficos
Autores principales: Kelly, Maia I., Albahrani, Mustafa, Castro, Chase, Poon, Ellen, Yan, Bin, Littrell, Jack, Waas, Matthew, Boheler, Kenneth R., Gundry, Rebekah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245383/
https://www.ncbi.nlm.nih.gov/pubmed/33830329
http://dx.doi.org/10.1007/s00424-021-02554-x

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