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Default polyfunctional T helper 1 response to ample signal 1 alone

CD4(+) T cells integrate well-defined signals from the T-cell receptor (TCR) (signal 1) and a host of costimulatory molecules (signal 2) to initiate clonal expansion and differentiation into diverse functional T helper (Th) subsets. However, our ability to guide the expansion of context-appropriate...

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Detalles Bibliográficos
Autores principales: Danelli, Luca, Cornish, Georgina, Merkenschlager, Julia, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245500/
https://www.ncbi.nlm.nih.gov/pubmed/32313208
http://dx.doi.org/10.1038/s41423-020-0415-x

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