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Default polyfunctional T helper 1 response to ample signal 1 alone
CD4(+) T cells integrate well-defined signals from the T-cell receptor (TCR) (signal 1) and a host of costimulatory molecules (signal 2) to initiate clonal expansion and differentiation into diverse functional T helper (Th) subsets. However, our ability to guide the expansion of context-appropriate...
Autores principales: | Danelli, Luca, Cornish, Georgina, Merkenschlager, Julia, Kassiotis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245500/ https://www.ncbi.nlm.nih.gov/pubmed/32313208 http://dx.doi.org/10.1038/s41423-020-0415-x |
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