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A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels

Stochastic gene expression leads to inherent variability in expression outcomes even in isogenic single-celled organisms grown in the same environment. The Drop-Seq technology facilitates transcriptomic studies of individual mammalian cells, and it has had transformative effects on the characterizat...

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Detalles Bibliográficos
Autores principales: Urbonaite, Guste, Lee, Jimmy Tsz Hang, Liu, Ping, Parada, Guillermo E., Hemberg, Martin, Acar, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245502/
https://www.ncbi.nlm.nih.gov/pubmed/34193958
http://dx.doi.org/10.1038/s42003-021-02320-w