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A yeast-optimized single-cell transcriptomics platform elucidates how mycophenolic acid and guanine alter global mRNA levels
Stochastic gene expression leads to inherent variability in expression outcomes even in isogenic single-celled organisms grown in the same environment. The Drop-Seq technology facilitates transcriptomic studies of individual mammalian cells, and it has had transformative effects on the characterizat...
Autores principales: | Urbonaite, Guste, Lee, Jimmy Tsz Hang, Liu, Ping, Parada, Guillermo E., Hemberg, Martin, Acar, Murat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245502/ https://www.ncbi.nlm.nih.gov/pubmed/34193958 http://dx.doi.org/10.1038/s42003-021-02320-w |
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