Multipotent adult progenitor cells induce regulatory T cells and promote their suppressive phenotype via TGFβ and monocyte-dependent mechanisms

Dysregulation of the immune system can initiate chronic inflammatory responses that exacerbate disease pathology. Multipotent adult progenitor cells (MAPC cells), an adult adherent bone-marrow derived stromal cell, have been observed to promote the resolution of uncontrolled inflammatory responses i...

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Detalles Bibliográficos
Autores principales: Valentin-Torres, Alice, Day, Cora, Taggart, Jennifer M., Williams, Nicholas, Stubblefield, Samantha R., Roobrouck, Valerie D., Beyens, Jelle, Ting, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245558/
https://www.ncbi.nlm.nih.gov/pubmed/34193955
http://dx.doi.org/10.1038/s41598-021-93025-x

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