Validating quantitative PCR assays for cfDNA detection without DNA extraction in exercising SLE patients

Circulating cell-free DNA (cfDNA) has been investigated as a screening tool for many diseases. To avoid expensive and time-consuming DNA isolation, direct quantification PCR assays can be established. However, rigorous validation is required to provide reliable data in the clinical and non-clinical...

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Detalles Bibliográficos
Autores principales: Neuberger, Elmo W. I., Brahmer, Alexandra, Ehlert, Tobias, Kluge, Katrin, Philippi, Keito F. A., Boedecker, Simone C., Weinmann-Menke, Julia, Simon, Perikles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245561/
https://www.ncbi.nlm.nih.gov/pubmed/34193884
http://dx.doi.org/10.1038/s41598-021-92826-4

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