Inhibition of HDAC6 Activity Protects Against Endothelial Dysfunction and Atherogenesis in vivo: A Role for HDAC6 Neddylation

We previously reported that histone deacetylase 6 (HDAC6) has an important role in endothelial cell (EC) function in vitro. However, whether HDAC6 plays a role in atherogenesis in vivo and the mechanism(s) that control HDAC6 activity/expression in response to atherogenic stimuli are unclear. The goa...

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Detalles Bibliográficos
Autores principales: Nomura, Yohei, Nakano, Mitsunori, Woo Sung, Hyun, Han, Mingming, Pandey, Deepesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245780/
https://www.ncbi.nlm.nih.gov/pubmed/34220539
http://dx.doi.org/10.3389/fphys.2021.675724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245780/
https://www.ncbi.nlm.nih.gov/pubmed/34220539
http://dx.doi.org/10.3389/fphys.2021.675724

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