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Extensive expansion of the chemical diversity of fusidane-type antibiotics using a stochastic combinational strategy
Fusidane-type antibiotics, represented by helvolic acid, fusidic acid and cephalosporin P(1), are fungi-derived antimicrobials with little cross-resistance to commonly used antibiotics. Generation of new fusidane-type derivatives is therefore of great value, but this is hindered by available approac...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245791/ https://www.ncbi.nlm.nih.gov/pubmed/34221876 http://dx.doi.org/10.1016/j.apsb.2020.12.007 |