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TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood

BACKGROUND: T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the T-cell receptor (TCR) repertoire in cerebrospinal fluid (CSF) of MS patients by h...

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Detalles Bibliográficos
Autores principales:	Amoriello, Roberta, Chernigovskaya, Maria, Greiff, Victor, Carnasciali, Alberto, Massacesi, Luca, Barilaro, Alessandro, Repice, Anna M., Biagioli, Tiziana, Aldinucci, Alessandra, Muraro, Paolo A., Laplaud, David A., Lossius, Andreas, Ballerini, Clara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245901/ https://www.ncbi.nlm.nih.gov/pubmed/34127432 http://dx.doi.org/10.1016/j.ebiom.2021.103429

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