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HYD-PEP06 suppresses hepatocellular carcinoma metastasis, epithelial–mesenchymal transition and cancer stem cell-like properties by inhibiting PI3K/AKT and WNT/β-catenin signaling activation

HYD-PEP06, an endostatin-modified polypeptide, has been shown to produce effective anti-colorectal carcinoma effects through inhibiting epithelial–mesenchymal transition (EMT). However, whether HYD-PEP06 has similar suppressive effect on hepatocellular carcinoma (HCC) remained unknown. In this study...

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Detalles Bibliográficos
Autores principales:	Tian, Wei, Li, Jiatong, Wang, Zhuo, Zhang, Tong, Han, Ying, Liu, Yanyan, Chu, Wenfeng, Liu, Yu, Yang, Baofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245914/ https://www.ncbi.nlm.nih.gov/pubmed/34221870 http://dx.doi.org/10.1016/j.apsb.2021.03.040

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