Cargando…
Expression of human‐specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility
Neocortex expansion during human evolution provides a basis for our enhanced cognitive abilities. Yet, which genes implicated in neocortex expansion are actually responsible for higher cognitive abilities is unknown. The expression of human‐specific ARHGAP11B in embryonic/foetal mouse, ferret and ma...
Autores principales: | Xing, Lei, Kubik‐Zahorodna, Agnieszka, Namba, Takashi, Pinson, Anneline, Florio, Marta, Prochazka, Jan, Sarov, Mihail, Sedlacek, Radislav, Huttner, Wieland B |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246068/ https://www.ncbi.nlm.nih.gov/pubmed/33938018 http://dx.doi.org/10.15252/embj.2020107093 |
Ejemplares similares
-
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex
por: Kalebic, Nereo, et al.
Publicado: (2018) -
Malformations of Human Neocortex in Development – Their Progenitor Cell Basis and Experimental Model Systems
por: Pinson, Anneline, et al.
Publicado: (2019) -
A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification
por: Florio, Marta, et al.
Publicado: (2016) -
Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex
por: Florio, Marta, et al.
Publicado: (2018) -
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex
por: Da Silva, Fabio, et al.
Publicado: (2021)