Elderly woman with a bleb leak

PURPOSE: To describe a unique incidence of inadvertent filtering bleb creation after intravitreal injections. OBSERVATIONS: An 84-year-old woman with a history of wet age-related macular degeneration requiring intravitreal injections presented with a Seidel-positive conjunctival cyst. The cyst was in an area where she had received multiple injections and was suspected to be an inadvertent filtering bleb secondary to a full-thickness scleral hole created by these injections. She underwent surgical closure of the fistula and repair of the bleb. CONCLUSIONS AND IMPORTANCE: This case emphasizes the importance of recognizing this potential complication of intraocular injections and outlines steps that should be taken to prevent poor outcomes and vision loss.