Cargando…

Irisin ameliorates nicotine-mediated atherosclerosis via inhibition of the PI3K pathway

BACKGROUND: Atherosclerosis is a chronic disease, with smoking being an independent risk factor. Irisin, a factor produced by myocytes, is expected to treat smoking-related arteriosclerosis, however its specific mechanism remains unclear. METHODS: Forty Apoe-/- mice with nicotine intervention were i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Kang, Chen, Junye, Wang, Chaonan, Shao, Jiang, Lai, Zhichao, Yu, Xiaoxi, Du, Fenghe, Gao, Ran, Wang, Jing, Liu, Bao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246167/ https://www.ncbi.nlm.nih.gov/pubmed/34268418 http://dx.doi.org/10.21037/atm-21-2072

Ejemplares similares

Irisin Suppresses Nicotine-Mediated Atherosclerosis by Attenuating Endothelial Cell Migration, Proliferation, Cell Cycle Arrest, and Cell Senescence
por: Chen, Junye, et al.
Publicado: (2022)

Renal perfusion improvement in the perioperative period after unilateral endovascular revascularization in patients with atherosclerotic renal artery stenosis
por: Xu, Leyin, et al.
Publicado: (2023)

Case report: Traumatic carotid artery dissection after 7D High-Intensity Macro- and Micro-Focused Ultrasound treatment for skin laxity of the neck
por: Du, Fenghe, et al.
Publicado: (2022)

A contrast-enhanced CT-based radiomic nomogram for the differential diagnosis of intravenous leiomyomatosis and uterine leiomyoma
por: Shao, Jiang, et al.
Publicado: (2023)

Long-term outcomes of conservative treatment and endovascular treatment in patients with symptomatic spontaneous isolated superior mesenteric artery dissection: a single-center experience
por: Xu, Leyin, et al.
Publicado: (2020)

Angiosome-directed endovascular intervention and infrapopliteal disease: Intraoperative evaluation of distal hemodynamic changes and foot blood volume of lower extremity
por: Wang, Chaonan, et al.
Publicado: (2022)

Irisin Inhibits Atherosclerosis by Promoting Endothelial Proliferation Through microRNA126‐5p
por: Zhang, Yuzhu, et al.
Publicado: (2016)

Irisin ameliorates age‐associated sarcopenia and metabolic dysfunction
por: Guo, Mingwei, et al.
Publicado: (2022)

The Potential Role of Irisin in Vascular Function and Atherosclerosis: A Review
por: Byun, Kyeongho, et al.
Publicado: (2020)

Irisin as a Novel Biomarker of Subclinical Atherosclerosis in Severe Obesity
por: Carmona-Maurici, Júlia, et al.
Publicado: (2023)

Nicotine in Senescence and Atherosclerosis
por: Centner, Ann Marie, et al.
Publicado: (2020)

Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin
por: Kam, Tae-In, et al.
Publicado: (2022)

Irisin Ameliorates Hypoxia/Reoxygenation-Induced Injury through Modulation of Histone Deacetylase 4
por: Zhao, Yu Tina, et al.
Publicado: (2016)

Irisin Enhances Angiogenesis of Mesenchymal Stem Cells to Promote Cardiac Function in Myocardial Infarction via PI3k/Akt Activation
por: Yang, Fan, et al.
Publicado: (2021)

Role of PI3K in the Progression and Regression of Atherosclerosis
por: Zhao, Yunyun, et al.
Publicado: (2021)

The Correlation of Apolipoprotein B with Alterations in Specific Fat Depots Content in Adults
por: Chen, Junye, et al.
Publicado: (2023)

Serum irisin and apelin levels and markers of atherosclerosis in patients with subclinical hypothyroidism
por: Yasar, Hamiyet Yilmaz, et al.
Publicado: (2019)

Novel myokine: irisin may be an independent predictor for subclinic atherosclerosis in Behçet's disease
por: Icli, Abdullah, et al.
Publicado: (2016)

Exists a role for serum irisin in Egyptian Behcet’s patients with subclinical atherosclerosis?
por: Ismail, Mohamed A., et al.
Publicado: (2022)

Irisin Gene Delivery Ameliorates Burn-Induced Sensory and Motor Neuropathy
por: Huang, Shu-Hung, et al.
Publicado: (2020)

Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice
por: Yang, Zhaohua, et al.
Publicado: (2023)

Irisin Ameliorates Intervertebral Disc Degeneration by Activating LATS/YAP/CTGF Signaling
por: Chen, Taiqiu, et al.
Publicado: (2022)

Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway
por: Liu, Jiayu, et al.
Publicado: (2019)

Irisin functions to inhibit malignant growth of human pancreatic cancer cells via downregulation of the PI3K/AKT signaling pathway
por: Zhang, Deguo, et al.
Publicado: (2019)

Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction
por: Zhang, Yuzhu, et al.
Publicado: (2016)

Irisin enhances chondrogenic differentiation of human mesenchymal stem cells via Rap1/PI3K/AKT axis
por: Chen, Taiqiu, et al.
Publicado: (2022)

Protective effect of irisin against Alzheimer’s disease
por: Chen, Kang, et al.
Publicado: (2022)

Irisin as a Novel Biomarker of Subclinical Atherosclerosis, Cardiovascular Risk and Severe Disease in Axial Spondyloarthritis
por: Remuzgo-Martínez, Sara, et al.
Publicado: (2022)

Irisin ameliorates myocardial ischemia-reperfusion injury by modulating gut microbiota and intestinal permeability in rats
por: Liu, Qingqing, et al.
Publicado: (2023)

Wen-Xin Decoction ameliorates vascular endothelium dysfunction via the PI3K/AKT/eNOS pathway in experimental atherosclerosis in rats
por: Li, Tongda, et al.
Publicado: (2016)

Role of irisin in physiology and pathology
por: Liu, Shiqiang, et al.
Publicado: (2022)

PET Imaging of the Human Nicotinic Cholinergic Pathway in Atherosclerosis
por: Bauwens, Matthias, et al.
Publicado: (2015)

Endothelial to mesenchymal transition contributes to nicotine-induced atherosclerosis
por: Qin, Wei, et al.
Publicado: (2020)

Berberine inhibited carotid atherosclerosis through PI3K/AKTmTOR signaling pathway
por: Song, Ting, et al.
Publicado: (2021)

Role of irisin in bone diseases
por: Zhao, Ruobing, et al.
Publicado: (2023)

AKAP12 ameliorates liver injury via targeting PI3K/AKT/PCSK6 pathway
por: Wu, Xuan, et al.
Publicado: (2022)

Comment on ‘Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice’ by Kawao et al.
por: Bao, Jing‐Fu, et al.
Publicado: (2022)

Irisin Ameliorated Skeletal Muscle Atrophy by Inhibiting Fatty Acid Oxidation and Pyroptosis Induced by Palmitic Acid in Chronic Kidney Disease
por: Zhou, Ting, et al.
Publicado: (2023)

PI3K inhibitor treatment ameliorates the glucocorticoid insensitivity of PBMCs in severe asthma
por: Bi, Jing, et al.
Publicado: (2020)

Updated Role of Neuropeptide Y in Nicotine-Induced Endothelial Dysfunction and Atherosclerosis
por: Zheng, Yan-li, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m465gtmeljrkl5hafg43ql38n2