Saturation mutagenesis defines novel mouse models of severe spine deformity

Embryonic formation and patterning of the vertebrate spinal column requires coordination of many molecular cues. After birth, the integrity of the spine is impacted by developmental abnormalities of the skeletal, muscular and nervous systems, which may result in deformities, such as kyphosis and sco...

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Detalles Bibliográficos
Autores principales: Rios, Jonathan J., Denton, Kristin, Yu, Hao, Manickam, Kandamurugu, Garner, Shannon, Russell, Jamie, Ludwig, Sara, Rosenfeld, Jill A., Liu, Pengfei, Munch, Jake, Sucato, Daniel J., Beutler, Bruce, Wise, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246263/
https://www.ncbi.nlm.nih.gov/pubmed/34142127
http://dx.doi.org/10.1242/dmm.048901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246263/
https://www.ncbi.nlm.nih.gov/pubmed/34142127
http://dx.doi.org/10.1242/dmm.048901

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