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IFN-γ- and IL-17-producing CD8(+) T (Tc17-1) cells in combination with poly-ICLC and peptide vaccine exhibit antiglioma activity

BACKGROUND: While adoptive transfer of T-cells has been a major medical breakthrough for patients with B cell malignancies, the development of safe and effective T-cell-based immunotherapy for central nervous system (CNS) tumors, such as glioblastoma (GBM), still needs to overcome multiple challenge...

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Detalles Bibliográficos
Autores principales:	Ohkuri, Takayuki, Kosaka, Akemi, Ikeura, Maki, Salazar, Andres M, Okada, Hideho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246372/ https://www.ncbi.nlm.nih.gov/pubmed/34193567 http://dx.doi.org/10.1136/jitc-2021-002426

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