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Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ

INTRODUCTION: Lemierre’s syndrome is a rare but serious complication of an oral infection mostly related to Fusobacterium necrophorum. This condition combines jugular vein thrombosis and septic emboli to the lungs or other organs. CASE PRESENTATION: We report here an original case of a pharyngeal ab...

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Autores principales: Barguil, Solène, Sousa Alves, Audrey, Christen, Jacques-Robert, De Jerphanion, Cécile, Valero, Joris, Gaillard, Tiphaine, Karkowski, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246386/
https://www.ncbi.nlm.nih.gov/pubmed/34235050
http://dx.doi.org/10.1016/j.idcr.2021.e01180
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author Barguil, Solène
Sousa Alves, Audrey
Christen, Jacques-Robert
De Jerphanion, Cécile
Valero, Joris
Gaillard, Tiphaine
Karkowski, Ludovic
author_facet Barguil, Solène
Sousa Alves, Audrey
Christen, Jacques-Robert
De Jerphanion, Cécile
Valero, Joris
Gaillard, Tiphaine
Karkowski, Ludovic
author_sort Barguil, Solène
collection PubMed
description INTRODUCTION: Lemierre’s syndrome is a rare but serious complication of an oral infection mostly related to Fusobacterium necrophorum. This condition combines jugular vein thrombosis and septic emboli to the lungs or other organs. CASE PRESENTATION: We report here an original case of a pharyngeal abscess complicated by Lemierre’s syndrome in a young healthy male patient. Samples taken from the pus of the pharyngeal abscess showed the presence of Gardnerella vaginalis associated with Fusobacterium necrophorum. The patient was treated by draining the abscess, antibiotic therapy and preventive anticoagulation for 1 month. The evolution was good with a resolution of the thrombosis. CONCLUSIONS: This case highlights the need for bacterial identification to adapt antibiotic therapy in Lemierre’s syndrome. It also shows the possibility of extragenital localization of Gardnerella vaginalis in a male patient having oral sex with women. In contrast to sexually transmitted infections such as syphilis and pharyngeal gonococcus, this oral localization of Gardnerella vaginalis has not been described previously in the literature.
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spelling pubmed-82463862021-07-06 Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ Barguil, Solène Sousa Alves, Audrey Christen, Jacques-Robert De Jerphanion, Cécile Valero, Joris Gaillard, Tiphaine Karkowski, Ludovic IDCases Case Report INTRODUCTION: Lemierre’s syndrome is a rare but serious complication of an oral infection mostly related to Fusobacterium necrophorum. This condition combines jugular vein thrombosis and septic emboli to the lungs or other organs. CASE PRESENTATION: We report here an original case of a pharyngeal abscess complicated by Lemierre’s syndrome in a young healthy male patient. Samples taken from the pus of the pharyngeal abscess showed the presence of Gardnerella vaginalis associated with Fusobacterium necrophorum. The patient was treated by draining the abscess, antibiotic therapy and preventive anticoagulation for 1 month. The evolution was good with a resolution of the thrombosis. CONCLUSIONS: This case highlights the need for bacterial identification to adapt antibiotic therapy in Lemierre’s syndrome. It also shows the possibility of extragenital localization of Gardnerella vaginalis in a male patient having oral sex with women. In contrast to sexually transmitted infections such as syphilis and pharyngeal gonococcus, this oral localization of Gardnerella vaginalis has not been described previously in the literature. Elsevier 2021-06-18 /pmc/articles/PMC8246386/ /pubmed/34235050 http://dx.doi.org/10.1016/j.idcr.2021.e01180 Text en © 2021 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Barguil, Solène
Sousa Alves, Audrey
Christen, Jacques-Robert
De Jerphanion, Cécile
Valero, Joris
Gaillard, Tiphaine
Karkowski, Ludovic
Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title_full Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title_fullStr Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title_full_unstemmed Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title_short Pharyngeal abscess complicated by Lemierre’s syndrome: Identification of an atypical germ
title_sort pharyngeal abscess complicated by lemierre’s syndrome: identification of an atypical germ
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246386/
https://www.ncbi.nlm.nih.gov/pubmed/34235050
http://dx.doi.org/10.1016/j.idcr.2021.e01180
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