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Targeted therapy in SDH-deficient GIST

The medical management of advanced gastrointestinal stromal tumors (GIST) has improved with the development of tyrosine kinase inhibitors (TKIs) targeting KIT and PDGFRA mutations. However, approximately 5–10% of GIST lack KIT and PDGFRA mutations, and about a half are deficient in succinate dehydro...

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Detalles Bibliográficos
Autores principales:	Nannini, Margherita, Rizzo, Alessandro, Indio, Valentina, Schipani, Angela, Astolfi, Annalisa, Pantaleo, Maria Abbondanza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246492/ https://www.ncbi.nlm.nih.gov/pubmed/34262616 http://dx.doi.org/10.1177/17588359211023278

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