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The Structural and Biochemical Characterization of UNC119B Cargo Binding and Release Mechanisms

[Image: see text] Two paralogs of the guanine dissociation inhibitor-like solubilizing factors UNC119, UNC119A and UNC119B, are present in the human genome. UNC119 binds to N-myristoylated proteins and masks the hydrophobic lipid from the hydrophilic cytosol, facilitating trafficking between differe...

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Detalles Bibliográficos
Autores principales:	Yelland, Tamas, Garcia, Esther, Samarakoon, Youhani, Ismail, Shehab
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246649/ https://www.ncbi.nlm.nih.gov/pubmed/34130453 http://dx.doi.org/10.1021/acs.biochem.1c00251

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