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STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose

BACKGROUND: Epithelial-mesenchymal transition (EMT) of mesothelial cells is a key step in the peritoneal fibrosis (PF). Recent evidence indicates that signal transducer and activator of transcription 3 (STAT3) might mediate the process of renal fibrosis, which could induce the expression of hypoxia-...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoxiao, Bao, Manchen, Fang, Yi, Yu, Xiaofang, Ji, Jun, Ding, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246671/
https://www.ncbi.nlm.nih.gov/pubmed/34193173
http://dx.doi.org/10.1186/s12967-021-02946-8

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