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STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose
BACKGROUND: Epithelial-mesenchymal transition (EMT) of mesothelial cells is a key step in the peritoneal fibrosis (PF). Recent evidence indicates that signal transducer and activator of transcription 3 (STAT3) might mediate the process of renal fibrosis, which could induce the expression of hypoxia-...
Autores principales: | Yang, Xiaoxiao, Bao, Manchen, Fang, Yi, Yu, Xiaofang, Ji, Jun, Ding, Xiaoqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246671/ https://www.ncbi.nlm.nih.gov/pubmed/34193173 http://dx.doi.org/10.1186/s12967-021-02946-8 |
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