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An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019

We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye...

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Autores principales: Toovey, Oliver T. R., Kulkarni, Priti, David, Joicy, Patel, Ayushi, Lai, Florence Y., Burns, Joyce, Thompson, Catherine, Ellis, Joanna, Tang, Julian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246710/
https://www.ncbi.nlm.nih.gov/pubmed/33135807
http://dx.doi.org/10.1002/jmv.26647
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author Toovey, Oliver T. R.
Kulkarni, Priti
David, Joicy
Patel, Ayushi
Lai, Florence Y.
Burns, Joyce
Thompson, Catherine
Ellis, Joanna
Tang, Julian W.
author_facet Toovey, Oliver T. R.
Kulkarni, Priti
David, Joicy
Patel, Ayushi
Lai, Florence Y.
Burns, Joyce
Thompson, Catherine
Ellis, Joanna
Tang, Julian W.
author_sort Toovey, Oliver T. R.
collection PubMed
description We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D.
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spelling pubmed-82467102021-07-02 An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019 Toovey, Oliver T. R. Kulkarni, Priti David, Joicy Patel, Ayushi Lai, Florence Y. Burns, Joyce Thompson, Catherine Ellis, Joanna Tang, Julian W. J Med Virol Short Communications We report a large epidemic (n = 126) of keratoconjunctivitis predominantly with two lineages of adenovirus (AdV) type D8 in patients seen in eye casualty between march and August 2019. Other AdV species identified by viral sequencing included B, C, and E. Despite various features of more severe eye disease being present, these were not significantly different between the different AdV species, with similar rates of pseudomembrane formation and keratitis observed in patients with AdV species B as for those with AdV species D. John Wiley and Sons Inc. 2020-12-17 2021-06 /pmc/articles/PMC8246710/ /pubmed/33135807 http://dx.doi.org/10.1002/jmv.26647 Text en © 2020 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Short Communications
Toovey, Oliver T. R.
Kulkarni, Priti
David, Joicy
Patel, Ayushi
Lai, Florence Y.
Burns, Joyce
Thompson, Catherine
Ellis, Joanna
Tang, Julian W.
An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title_full An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title_fullStr An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title_full_unstemmed An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title_short An outbreak of adenovirus D8 keratoconjunctivitis in Leicester, United Kingdom, from March to August 2019
title_sort outbreak of adenovirus d8 keratoconjunctivitis in leicester, united kingdom, from march to august 2019
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246710/
https://www.ncbi.nlm.nih.gov/pubmed/33135807
http://dx.doi.org/10.1002/jmv.26647
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