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Extrachromosomal DNA amplicons in antimalarial‐resistant Plasmodium falciparum
Extrachromosomal (ec) DNAs are genetic elements that exist separately from the genome. Since ecDNA can carry beneficial genes, they are a powerful adaptive mechanism in cancers and many pathogens. For the first time, we report ecDNA contributing to antimalarial resistance in Plasmodium falciparum, t...
Autores principales: | McDaniels, Jennifer M., Huckaby, Adam C., Carter, Sabrina A., Lingeman, Sabrina, Francis, Audrey, Congdon, Molly, Santos, Webster, Rathod, Pradipsinh K., Guler, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246734/ https://www.ncbi.nlm.nih.gov/pubmed/33053232 http://dx.doi.org/10.1111/mmi.14624 |
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