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Thorough QT/QTc Study Evaluating the Effect of Macimorelin on Cardiac Safety Parameters in Healthy Participants

Macimorelin is an orally active growth hormone secretagogue indicated for the diagnosis of adult growth hormone deficiency. The primary objective of this study was to evaluate the effect of macimorelin on the baseline and placebo‐corrected mean QT interval using Fridericia's formula (ΔΔQTcF). S...

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Detalles Bibliográficos
Autores principales: Lissy, Michael, Demmel, Valentin, Sachse, Richard, Ammer, Nicola, Kelepouris, Nicky, Ostrow, Vlady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246819/
https://www.ncbi.nlm.nih.gov/pubmed/32961034
http://dx.doi.org/10.1002/cpdd.872