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Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex

The formyl peptide receptors FPR1 and FPR2 are abundantly expressed by neutrophils, in which they regulate proinflammatory tissue recruitment of inflammatory cells, the production of reactive oxygen species (ROS), and resolution of inflammatory reactions. The unique dual functionality of the FPRs ma...

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Detalles Bibliográficos
Autores principales: Lind, Simon, Dahlgren, Claes, Holmdahl, Rikard, Olofsson, Peter, Forsman, Huamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246850/
https://www.ncbi.nlm.nih.gov/pubmed/33040403
http://dx.doi.org/10.1002/JLB.2HI0520-317R