Characterization of the substrate binding site of an iron detoxifying membrane transporter from Plasmodium falciparum

BACKGROUND: Plasmodium species are entirely dependent upon their host as a source of essential iron. Although it is an indispensable micronutrient, oxidation of excess ferrous iron to the ferric state in the cell cytoplasm can produce reactive oxygen species that are cytotoxic. The malaria parasite...

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Detalles Bibliográficos
Autores principales: Sharma, Pragya, Tóth, Veronika, Hyland, Edel M., Law, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247066/
https://www.ncbi.nlm.nih.gov/pubmed/34193175
http://dx.doi.org/10.1186/s12936-021-03827-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247066/
https://www.ncbi.nlm.nih.gov/pubmed/34193175
http://dx.doi.org/10.1186/s12936-021-03827-7

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