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Insertion of an endogenous Jaagsiekte sheep retrovirus element into the BCO2 - gene abolishes its function and leads to yellow discoloration of adipose tissue in Norwegian Spælsau (Ovis aries)

BACKGROUND: The accumulation of carotenoids in adipose tissue leading to yellow fat is, in sheep, a heritable recessive trait that can be attributed to a nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene. However, not all sheep breeds suffering from yellow fat have this nonsense mutatio...

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Detalles Bibliográficos
Autores principales: Kent, Matthew, Moser, Michel, Boman, Inger Anne, Lindtveit, Kristine, Árnyasi, Mariann, Sundsaasen, Kristil Kindem, Våge, Dag Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247158/
https://www.ncbi.nlm.nih.gov/pubmed/34193038
http://dx.doi.org/10.1186/s12864-021-07826-5