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SMOOTH-seq: single-cell genome sequencing of human cells on a third-generation sequencing platform

There is no effective way to detect structure variations (SVs) and extra-chromosomal circular DNAs (ecDNAs) at single-cell whole-genome level. Here, we develop a novel third-generation sequencing platform-based single-cell whole-genome sequencing (scWGS) method named SMOOTH-seq (single-molecule real...

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Detalles Bibliográficos
Autores principales:	Fan, Xiaoying, Yang, Cheng, Li, Wen, Bai, Xiuzhen, Zhou, Xin, Xie, Haoling, Wen, Lu, Tang, Fuchou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247186/ https://www.ncbi.nlm.nih.gov/pubmed/34193237 http://dx.doi.org/10.1186/s13059-021-02406-y

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