Humanized liver mouse model with transplanted human hepatocytes from patients with ornithine transcarbamylase deficiency

Ornithine transcarbamylase deficiency (OTCD) is a metabolic and genetic disease caused by dysfunction of the hepatocytic urea cycle. To develop new drugs or therapies for OTCD, it is ideal to use models that are more closely related to human metabolism and pathology. Primary human hepatocytes (HHs)...

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Detalles Bibliográficos
Autores principales: Sugahara, Go, Yamasaki, Chihiro, Yanagi, Ami, Furukawa, Suzue, Ogawa, Yuko, Fukuda, Akinari, Enosawa, Shin, Umezawa, Akihiro, Ishida, Yuji, Tateno, Chise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247293/
https://www.ncbi.nlm.nih.gov/pubmed/33336822
http://dx.doi.org/10.1002/jimd.12347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247293/
https://www.ncbi.nlm.nih.gov/pubmed/33336822
http://dx.doi.org/10.1002/jimd.12347

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