Identification of gene targets of developmental neurotoxicity focusing on DNA hypermethylation involved in irreversible disruption of hippocampal neurogenesis in rats

We have previously found that maternal exposure to 6‐propyl‐2‐thiouracil (PTU), valproic acid (VPA), or glycidol (GLY) has a sustained or late effect on hippocampal neurogenesis at the adult stage in rat offspring. Herein, we searched for genes with hypermethylated promoter region and downregulated...

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Detalles Bibliográficos
Autores principales: Kikuchi, Satomi, Takahashi, Yasunori, Ojiro, Ryota, Takashima, Kazumi, Okano, Hiromu, Tang, Qian, Woo, Gye‐Hyeong, Yoshida, Toshinori, Shibutani, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247304/
https://www.ncbi.nlm.nih.gov/pubmed/33150595
http://dx.doi.org/10.1002/jat.4089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247304/
https://www.ncbi.nlm.nih.gov/pubmed/33150595
http://dx.doi.org/10.1002/jat.4089

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