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Identification of gene targets of developmental neurotoxicity focusing on DNA hypermethylation involved in irreversible disruption of hippocampal neurogenesis in rats
We have previously found that maternal exposure to 6‐propyl‐2‐thiouracil (PTU), valproic acid (VPA), or glycidol (GLY) has a sustained or late effect on hippocampal neurogenesis at the adult stage in rat offspring. Herein, we searched for genes with hypermethylated promoter region and downregulated...
Autores principales: | Kikuchi, Satomi, Takahashi, Yasunori, Ojiro, Ryota, Takashima, Kazumi, Okano, Hiromu, Tang, Qian, Woo, Gye‐Hyeong, Yoshida, Toshinori, Shibutani, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247304/ https://www.ncbi.nlm.nih.gov/pubmed/33150595 http://dx.doi.org/10.1002/jat.4089 |
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