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Emerging Diagnostic Potential of Tumor-derived Exosomes
Exosomes carry genetic information originating from their parental cells, raising their possibility as novel noninvasive biomarkers for cancer. Tumor-derived exosomes (TEXs) have a variety of endogenous cargos that reflect the pathophysiology status and information of tumor cells. TEXs are increasin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247367/ https://www.ncbi.nlm.nih.gov/pubmed/34234872 http://dx.doi.org/10.7150/jca.59391 |
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author | Luo, Ruhua Liu, Mengmeng Yang, Qian Cheng, Huijuan Yang, Huimin Li, Minhui Bai, Xue Wang, Yue Zhang, Honghua Wang, Shuling Xie, Tian Tian, Qingchang |
author_facet | Luo, Ruhua Liu, Mengmeng Yang, Qian Cheng, Huijuan Yang, Huimin Li, Minhui Bai, Xue Wang, Yue Zhang, Honghua Wang, Shuling Xie, Tian Tian, Qingchang |
author_sort | Luo, Ruhua |
collection | PubMed |
description | Exosomes carry genetic information originating from their parental cells, raising their possibility as novel noninvasive biomarkers for cancer. Tumor-derived exosomes (TEXs) have a variety of endogenous cargos that reflect the pathophysiology status and information of tumor cells. TEXs are increasingly being recognized as potential biomarkers for cancer diagnosis prognosis, and monitoring. It is important to develop a variety of sensitive methods, including probes and biomaterials to isolate exosomes. A variety of approaches for detecting exosomes have been established. By combining exosome DNA and RNA sequencing tools, exosome proteomics analysis and immunoassay technology, it is expected that exosomes will gain widespread use in the diagnosis and treatment of cancer. |
format | Online Article Text |
id | pubmed-8247367 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Ivyspring International Publisher |
record_format | MEDLINE/PubMed |
spelling | pubmed-82473672021-07-06 Emerging Diagnostic Potential of Tumor-derived Exosomes Luo, Ruhua Liu, Mengmeng Yang, Qian Cheng, Huijuan Yang, Huimin Li, Minhui Bai, Xue Wang, Yue Zhang, Honghua Wang, Shuling Xie, Tian Tian, Qingchang J Cancer Review Exosomes carry genetic information originating from their parental cells, raising their possibility as novel noninvasive biomarkers for cancer. Tumor-derived exosomes (TEXs) have a variety of endogenous cargos that reflect the pathophysiology status and information of tumor cells. TEXs are increasingly being recognized as potential biomarkers for cancer diagnosis prognosis, and monitoring. It is important to develop a variety of sensitive methods, including probes and biomaterials to isolate exosomes. A variety of approaches for detecting exosomes have been established. By combining exosome DNA and RNA sequencing tools, exosome proteomics analysis and immunoassay technology, it is expected that exosomes will gain widespread use in the diagnosis and treatment of cancer. Ivyspring International Publisher 2021-06-16 /pmc/articles/PMC8247367/ /pubmed/34234872 http://dx.doi.org/10.7150/jca.59391 Text en © The author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. |
spellingShingle | Review Luo, Ruhua Liu, Mengmeng Yang, Qian Cheng, Huijuan Yang, Huimin Li, Minhui Bai, Xue Wang, Yue Zhang, Honghua Wang, Shuling Xie, Tian Tian, Qingchang Emerging Diagnostic Potential of Tumor-derived Exosomes |
title | Emerging Diagnostic Potential of Tumor-derived Exosomes |
title_full | Emerging Diagnostic Potential of Tumor-derived Exosomes |
title_fullStr | Emerging Diagnostic Potential of Tumor-derived Exosomes |
title_full_unstemmed | Emerging Diagnostic Potential of Tumor-derived Exosomes |
title_short | Emerging Diagnostic Potential of Tumor-derived Exosomes |
title_sort | emerging diagnostic potential of tumor-derived exosomes |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247367/ https://www.ncbi.nlm.nih.gov/pubmed/34234872 http://dx.doi.org/10.7150/jca.59391 |
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