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Mitochondrial DNA copy number in human disease: the more the better?

Most of the genetic information has been lost or transferred to the nucleus during the evolution of mitochondria. Nevertheless, mitochondria have retained their own genome that is essential for oxidative phosphorylation (OXPHOS). In mammals, a gene‐dense circular mitochondrial DNA (mtDNA) of about 1...

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Detalles Bibliográficos
Autores principales:	Filograna, Roberta, Mennuni, Mara, Alsina, David, Larsson, Nils‐Göran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247411/ https://www.ncbi.nlm.nih.gov/pubmed/33314045 http://dx.doi.org/10.1002/1873-3468.14021

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