Cargando…

Multimorbidity burden and dementia risk in older adults: The role of inflammation and genetics

INTRODUCTION: We investigate dementia risk in older adults with different disease patterns and explore the role of inflammation and apolipoprotein E (APOE) genotype. METHODS: A total of 2,478 dementia‐free participants with two or more chronic diseases (ie, multimorbidity) part of the Swedish Nation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grande, Giulia, Marengoni, Alessandra, Vetrano, Davide L., Roso‐Llorach, Albert, Rizzuto, Debora, Zucchelli, Alberto, Qiu, Chengxuan, Fratiglioni, Laura, Calderón‐Larrañaga, Amaia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Featured Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247430/ https://www.ncbi.nlm.nih.gov/pubmed/33403740 http://dx.doi.org/10.1002/alz.12237

Ejemplares similares

Multimorbidity Patterns and Unplanned Hospitalisation in a Cohort of Older Adults
por: Akugizibwe, Roselyne, et al.
Publicado: (2020)

TWELVE-YEAR CLINICAL TRAJECTORIES OF MULTIMORBIDITY IN OLDER ADULTS: A POPULATION-BASED STUDY
por: Vetrano, Davide Liborio, et al.
Publicado: (2019)

COMPARING THE PROGNOSTIC VALUE OF GERIATRIC HEALTH INDICATORS: A POPULATION-BASED STUDY
por: Zucchelli, Alberto, et al.
Publicado: (2019)

Comparing the prognostic value of geriatric health indicators: a population-based study
por: Zucchelli, Alberto, et al.
Publicado: (2019)

Multimorbidity patterns and risk of frailty in older community-dwelling adults: a population-based cohort study
por: Tazzeo, Clare, et al.
Publicado: (2021)

Twelve-year clinical trajectories of multimorbidity in a population of older adults
por: Vetrano, Davide L., et al.
Publicado: (2020)

Patterns of multimorbidity and risk of disability in community-dwelling older persons
por: Marengoni, Alessandra, et al.
Publicado: (2021)

A GENETIC ALGORITHM-BASED APPROACH TO OPTIMIZE THE CONSTRUCTION OF A FRAILTY INDEX
por: Zucchelli, Alberto, et al.
Publicado: (2019)

Trajectories of functional decline in older adults with neuropsychiatric and cardiovascular multimorbidity: A Swedish cohort study
por: Vetrano, Davide L., et al.
Publicado: (2018)

Health Trajectories in Swedish Centenarians
por: Vetrano, Davide L, et al.
Publicado: (2020)

Using a genetic algorithm to derive a highly predictive and context-specific frailty index
por: Zucchelli, Alberto, et al.
Publicado: (2020)

12-year evolution of multimorbidity patterns among older adults based on Hidden Markov Models
por: Roso-Llorach, Albert, et al.
Publicado: (2022)

Cognitive and physical markers of prodromal dementia: A 12‐year‐long population study
por: Grande, Giulia, et al.
Publicado: (2020)

Psychological correlates of multimorbidity and disability accumulation in older adults
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2019)

An International Perspective on Chronic Multimorbidity: Approaching the Elephant in the Room
por: Vetrano, Davide L, et al.
Publicado: (2018)

Special Issue—“Multimorbidity Development and Evolution: Clinical Implications”
por: Zucchelli, Alberto, et al.
Publicado: (2021)

Role of Orthostatic Hypotension in the Development of Dementia in People With and Without Cardiovascular Disease
por: Xia, Xin, et al.
Publicado: (2023)

Impact of Pneumonia on Cognitive Aging: A Longitudinal Propensity-Matched Cohort Study
por: Hendel, Merle K, et al.
Publicado: (2022)

Beyond Chronological Age: A Multidimensional Approach to Survival Prediction in Older Adults
por: Salignon, Jérôme, et al.
Publicado: (2022)

Specific multimorbidity patterns modify the impact of an exercise intervention in older hospitalized adults
por: Martínez-Velilla, Nicolas, et al.
Publicado: (2022)

Health trajectories after age 60: the role of individual behaviours and social contexts
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2021)

The Influence of Multimorbidity on Clinical Progression of Dementia in a Population-Based Cohort
por: Melis, René J. F., et al.
Publicado: (2013)

High excess mortality in areas with young and socially vulnerable populations during the COVID-19 outbreak in Stockholm Region, Sweden
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2020)

Health trajectories after age 60: the role of individual behaviors and the social context
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2021)

Association of Homocysteine, Methionine, and MTHFR 677C>T Polymorphism With Rate of Cardiovascular Multimorbidity Development in Older Adults in Sweden
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2020)

Beyond Chronological Age: Frailty and Multimorbidity Predict In-Hospital Mortality in Patients With COVID-19
por: Zucchelli, Alberto, et al.
Publicado: (2021)

Assessing and Measuring Chronic Multimorbidity in the Older Population: A Proposal for Its Operationalization
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2017)

Late-life depression and multimorbidity trajectories: the role of symptom complexity and severity
por: Triolo, Federico, et al.
Publicado: (2023)

Defining Health Trajectories in Older Adults With Five Clinical Indicators
por: Santoni, Giola, et al.
Publicado: (2017)

Glutathione Serum Levels and Rate of Multimorbidity Development in Older Adults
por: Pérez, Laura M, et al.
Publicado: (2020)

From Normal Cognition to Cognitive Impairment and Dementia: Impact of Orthostatic Hypotension
por: Xia, Xin, et al.
Publicado: (2021)

Association of Long-term Exposure to Air Pollution and Dementia Risk: The Role of Homocysteine, Methionine, and Cardiovascular Burden
por: Grande, Giulia, et al.
Publicado: (2023)

COVID-19 collateral damage—psychological burden and behavioural changes among older adults during the first outbreak in Stockholm, Sweden: a cross-sectional study
por: Beridze, Giorgi, et al.
Publicado: (2022)

Frailty detection among primary care older patients through the Primary Care Frailty Index (PC-FI)
por: Vetrano, Davide Liborio, et al.
Publicado: (2023)

Disease or function? What matters most for self-rated health in older people depends on age
por: Straatmann, Viviane S., et al.
Publicado: (2020)

Frailty, multimorbidity patterns and mortality in institutionalized older adults in Italy
por: Damiano, Cecilia, et al.
Publicado: (2022)

Concordance and Discrepancies Among 5 Creatinine-Based Equations for Assessing Estimated Glomerular Filtration Rate in Older Adults
por: Beridze, Giorgi, et al.
Publicado: (2023)

COVID-19: risk accumulation among biologically and socially vulnerable older populations
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2020)

Trajectories of Body Mass Index and Multimorbidity in Old Age: 12-Year Results From a Population-Based Study
por: Calderón-Larrañaga, Amaia, et al.
Publicado: (2021)

Cardiometabolic multimorbidity and incident dementia: the Swedish twin registry
por: Dove, Abigail, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_b5flonamv1n29vt0jc2i044jph