Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy

Immunoglobulin A (IgA) nephropathy is a heterogeneous disease with variable clinical presentations ranging from asymptomatic hematuria to advanced renal failure. A young male diagnosed with IgA vasculitis (skin, joints, and gastrointestinal) one month ago and placed on oral steroids presented with a...

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Autores principales: Saibaba, Jayaram, Selvaraj, Jayachandran, Viswanathan, Stalin, Pillai, Vivekanandan, Srinivas, Bheemanathi H, Mandal, Jharna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247609/
https://www.ncbi.nlm.nih.gov/pubmed/34239797
http://dx.doi.org/10.7759/cureus.15369
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author Saibaba, Jayaram
Selvaraj, Jayachandran
Viswanathan, Stalin
Pillai, Vivekanandan
Srinivas, Bheemanathi H
Mandal, Jharna
author_facet Saibaba, Jayaram
Selvaraj, Jayachandran
Viswanathan, Stalin
Pillai, Vivekanandan
Srinivas, Bheemanathi H
Mandal, Jharna
author_sort Saibaba, Jayaram
collection PubMed
description Immunoglobulin A (IgA) nephropathy is a heterogeneous disease with variable clinical presentations ranging from asymptomatic hematuria to advanced renal failure. A young male diagnosed with IgA vasculitis (skin, joints, and gastrointestinal) one month ago and placed on oral steroids presented with acute diarrhea, hemolytic anemia, renal failure (non-dialysis requiring), altered sensorium, and thrombocytopenia. The stool was found to be positive for Shiga toxin. He improved with methylprednisolone pulse alone, and renal biopsy showed acute tubular injury.
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spelling pubmed-82476092021-07-07 Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy Saibaba, Jayaram Selvaraj, Jayachandran Viswanathan, Stalin Pillai, Vivekanandan Srinivas, Bheemanathi H Mandal, Jharna Cureus Internal Medicine Immunoglobulin A (IgA) nephropathy is a heterogeneous disease with variable clinical presentations ranging from asymptomatic hematuria to advanced renal failure. A young male diagnosed with IgA vasculitis (skin, joints, and gastrointestinal) one month ago and placed on oral steroids presented with acute diarrhea, hemolytic anemia, renal failure (non-dialysis requiring), altered sensorium, and thrombocytopenia. The stool was found to be positive for Shiga toxin. He improved with methylprednisolone pulse alone, and renal biopsy showed acute tubular injury. Cureus 2021-06-01 /pmc/articles/PMC8247609/ /pubmed/34239797 http://dx.doi.org/10.7759/cureus.15369 Text en Copyright © 2021, Saibaba et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Saibaba, Jayaram
Selvaraj, Jayachandran
Viswanathan, Stalin
Pillai, Vivekanandan
Srinivas, Bheemanathi H
Mandal, Jharna
Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title_full Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title_fullStr Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title_full_unstemmed Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title_short Diarrhea and Acute Tubular Necrosis Mimicking Hemolytic Uremic Syndrome in a Man With Immunoglobulin A (IgA) Nephropathy
title_sort diarrhea and acute tubular necrosis mimicking hemolytic uremic syndrome in a man with immunoglobulin a (iga) nephropathy
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247609/
https://www.ncbi.nlm.nih.gov/pubmed/34239797
http://dx.doi.org/10.7759/cureus.15369
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