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Oral administration of amphotericin B nanoparticles: antifungal activity, bioavailability and toxicity in rats
Amphotericin B (AMB) is used most commonly in severe systemic life-threatening fungal infections. There is currently an unmet need for an efficacious (AMB) formulation amenable to oral administration with better bioavailability and lower nephrotoxicity. Novel PEGylated polylactic-polyglycolic acid c...
Autores principales: | Radwan, Mahasen A., AlQuadeib, Bushra T., Šiller, Lidija, Wright, Matthew C., Horrocks, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247729/ https://www.ncbi.nlm.nih.gov/pubmed/28155565 http://dx.doi.org/10.1080/10717544.2016.1228715 |
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