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Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses

[Image: see text] A class of pyrimidine thioglycoside analogs (6a–h) were synthesized from a reaction of 2-cyano-3,3-dimercapto-N-arylacrylamide (2a–d) and thiourea to produce the corresponding 4-amino-2-mercapto-N-arylpyrimidine-5-carboxamide derivatives (3a–d), and stirring of compounds (3a–d) wit...

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Detalles Bibliográficos
Autores principales: Abu-Zaied, Mamdouh A., Elgemeie, Galal H., Mahmoud, Nashwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247785/
https://www.ncbi.nlm.nih.gov/pubmed/34250348
http://dx.doi.org/10.1021/acsomega.1c01501