Cargando…
Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses
[Image: see text] A class of pyrimidine thioglycoside analogs (6a–h) were synthesized from a reaction of 2-cyano-3,3-dimercapto-N-arylacrylamide (2a–d) and thiourea to produce the corresponding 4-amino-2-mercapto-N-arylpyrimidine-5-carboxamide derivatives (3a–d), and stirring of compounds (3a–d) wit...
Autores principales: | Abu-Zaied, Mamdouh A., Elgemeie, Galal H., Mahmoud, Nashwa M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247785/ https://www.ncbi.nlm.nih.gov/pubmed/34250348 http://dx.doi.org/10.1021/acsomega.1c01501 |
Ejemplares similares
-
Toward Developing Therapies against Corona Virus:
Synthesis and Anti-Avian Influenza Virus Activity of Novel Cytosine
Thioglycoside Analogues
por: Abu-Zaied, Mamdouh A., et al.
Publicado: (2020) -
Sofosbuvir Thio-analogues: Synthesis and Antiviral
Evaluation of the First Novel Pyridine- and Pyrimidine-Based Thioglycoside
Phosphoramidates
por: Abu-Zaied, Mamdouh Attia, et al.
Publicado: (2020) -
Novel purine thioglycoside analogs: synthesis, nanoformulation and biological evaluation in in vitro human liver and breast cancer models
por: Abu-Zaied, Mamdouh A, et al.
Publicado: (2019) -
Crystal structure of 4,6-dimethyl-2-[(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)sulfanyl]pyrimidine
por: Abu-Zaied, Mamdouh A., et al.
Publicado: (2019) -
Novel Thiophene
Thioglycosides Substituted with the
Benzothiazole Moiety: Synthesis, Characterization, Antiviral and Anticancer Evaluations, and NS3/4A and USP7
Enzyme Inhibitions
por: Azzam, Rasha A., et al.
Publicado: (2022)