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An Artificial Cofactor Catalyzing the Baylis‐Hillman Reaction with Designed Streptavidin as Protein Host

An artificial cofactor based on an organocatalyst embedded in a protein has been used to conduct the Baylis‐Hillman reaction in a buffered system. As protein host, we chose streptavidin, as it can be easily crystallized and thereby supports the design process. The protein host around the cofactor wa...

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Detalles Bibliográficos
Autores principales: Lechner, Horst, Emann, Vincent R., Breuning, M., Höcker, Birte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247847/
https://www.ncbi.nlm.nih.gov/pubmed/33400831
http://dx.doi.org/10.1002/cbic.202000880