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An Artificial Cofactor Catalyzing the Baylis‐Hillman Reaction with Designed Streptavidin as Protein Host
An artificial cofactor based on an organocatalyst embedded in a protein has been used to conduct the Baylis‐Hillman reaction in a buffered system. As protein host, we chose streptavidin, as it can be easily crystallized and thereby supports the design process. The protein host around the cofactor wa...
Autores principales: | Lechner, Horst, Emann, Vincent R., Breuning, M., Höcker, Birte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247847/ https://www.ncbi.nlm.nih.gov/pubmed/33400831 http://dx.doi.org/10.1002/cbic.202000880 |
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