Divergent, Strain‐Release Reactions of Azabicyclo[1.1.0]butyl Carbinols: Semipinacol or Spiroepoxy Azetidine Formation

The azetidine moiety is a privileged motif in medicinal chemistry and new methods that access them efficiently are highly sought after. Towards this goal, we have found that azabicyclo[1.1.0]butyl carbinols, readily obtained from the highly strained azabicyclo[1.1.0]butane (ABB), can undergo diverge...

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Detalles Bibliográficos
Autores principales: Gregson, Charlotte H. U., Noble, Adam, Aggarwal, Varinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247891/
https://www.ncbi.nlm.nih.gov/pubmed/33555105
http://dx.doi.org/10.1002/anie.202100583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247891/
https://www.ncbi.nlm.nih.gov/pubmed/33555105
http://dx.doi.org/10.1002/anie.202100583

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