Prolonged survival after laser interstitial thermal therapy in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Management includes surgical resection followed by chemoradiation, and prognosis remains poor. Surgical resection is not possible for some deep-seated or eloquent tumors. Laser interstitial thermal therapy (LI...

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Autores principales: Khan, A. Basit, Matsuoka, Carlos Kamiya, Lee, Sungho, Rahman, Maryam, Rao, Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248111/
https://www.ncbi.nlm.nih.gov/pubmed/34221559
http://dx.doi.org/10.25259/SNI_174_2021
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author Khan, A. Basit
Matsuoka, Carlos Kamiya
Lee, Sungho
Rahman, Maryam
Rao, Ganesh
author_facet Khan, A. Basit
Matsuoka, Carlos Kamiya
Lee, Sungho
Rahman, Maryam
Rao, Ganesh
author_sort Khan, A. Basit
collection PubMed
description BACKGROUND: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Management includes surgical resection followed by chemoradiation, and prognosis remains poor. Surgical resection is not possible for some deep-seated or eloquent tumors. Laser interstitial thermal therapy (LITT) has emerged as a new, minimally invasive surgical option for deep-seated GBM. CASE DESCRIPTION: We report a case of newly diagnosed thalamic GBM managed with LITT followed by radiation and chemotherapy. CONCLUSION: The patient remains well at 50-month post-LITT, indicating a potentially unique durability of LITT treatment in GBM.
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spelling pubmed-82481112021-07-02 Prolonged survival after laser interstitial thermal therapy in glioblastoma Khan, A. Basit Matsuoka, Carlos Kamiya Lee, Sungho Rahman, Maryam Rao, Ganesh Surg Neurol Int Case Report BACKGROUND: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Management includes surgical resection followed by chemoradiation, and prognosis remains poor. Surgical resection is not possible for some deep-seated or eloquent tumors. Laser interstitial thermal therapy (LITT) has emerged as a new, minimally invasive surgical option for deep-seated GBM. CASE DESCRIPTION: We report a case of newly diagnosed thalamic GBM managed with LITT followed by radiation and chemotherapy. CONCLUSION: The patient remains well at 50-month post-LITT, indicating a potentially unique durability of LITT treatment in GBM. Scientific Scholar 2021-05-17 /pmc/articles/PMC8248111/ /pubmed/34221559 http://dx.doi.org/10.25259/SNI_174_2021 Text en Copyright: © 2021 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Khan, A. Basit
Matsuoka, Carlos Kamiya
Lee, Sungho
Rahman, Maryam
Rao, Ganesh
Prolonged survival after laser interstitial thermal therapy in glioblastoma
title Prolonged survival after laser interstitial thermal therapy in glioblastoma
title_full Prolonged survival after laser interstitial thermal therapy in glioblastoma
title_fullStr Prolonged survival after laser interstitial thermal therapy in glioblastoma
title_full_unstemmed Prolonged survival after laser interstitial thermal therapy in glioblastoma
title_short Prolonged survival after laser interstitial thermal therapy in glioblastoma
title_sort prolonged survival after laser interstitial thermal therapy in glioblastoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248111/
https://www.ncbi.nlm.nih.gov/pubmed/34221559
http://dx.doi.org/10.25259/SNI_174_2021
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AT rahmanmaryam prolongedsurvivalafterlaserinterstitialthermaltherapyinglioblastoma
AT raoganesh prolongedsurvivalafterlaserinterstitialthermaltherapyinglioblastoma

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